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1

Acetone potentiation of chronic liver injury induced by repetitive administration of carbon tetrachloride

Michel Charbonneau, Beatriz Tuchweber, Gabriel L. Plaa

Journal:

Year:

1986

Language:

english

File:

PDF, 844 KB

english, 1986

2

Chlorinated Methanes and Liver Injury: Highlights of the Past 50 Years

Plaa, Gabriel L.

Journal:

Annual Review of Pharmacology

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

3

Metabolic Alterations in Organ Function

Plaa, Gabriel L

Journal:

Journal of AOAC International

Year:

1975

File:

PDF, 689 KB

1975

4

Dose-response relationships in 1,3-butanediol-induced potentiation of carbon tetrachloride toxicity

William R. Hewitt, Hiroaki Miyajima, Michel G. Côté, L. Arthur Hewitt, Denis J. Cianflone, Gàbriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1982

Language:

english

File:

PDF, 2.02 MB

english, 1982

5

Hepatocellular membrane alteration as a possible cause of manganese-bilirubin-induced cholestasis

Eve De Lamirande, Beatriz Tuchweber, Gabriel L. Plaa

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 899 KB

english, 1981

6

Carbon Tetrachloride Hepatotoxicity: An Example of Lethal Cleavage

Rechnagel, Richard O., Glende, Eric A., Plaa, Gabriel L.

Journal:

Critical Reviews in Toxicology

Year:

1973

Language:

english

File:

PDF, 2.81 MB

english, 1973

7

Chlorinated Hydrocarbon Toxicity

Traiger, George J., Plaa, Gabriel L.

Journal:

Archives of Environmental Health An International Journal

Year:

1974

Language:

english

File:

PDF, 358 KB

english, 1974

8

Plasma Concentrations in Methyl Isobutyl Ketone-Potentiated Experimental Cholestasis after Inhalation or Oral Administration

Alexandra B. Duguay, Gabriel L. Plaa

Journal:

Fundamental and Applied Toxicology

Year:

1993

File:

PDF, 353 KB

1993

9

The induction of benzpyrene hydroxylase in the isolated perfused rat liver

Mont R. Juchau, Richard L. Cram, Gabriel L. Plaa, James R. Fouts

Journal:

Biochemical Pharmacology

Year:

1965

Language:

english

File:

PDF, 821 KB

english, 1965

10

Effect of norethandrolone on the biliary excretion of bilirubin in the mouse and rat

Robert J. Roberts, Sharon L. Shriver, Gabriel L. Plaa

Journal:

Biochemical Pharmacology

Year:

1968

Language:

english

File:

PDF, 591 KB

english, 1968

11

The effect of α-naphthylisothiocyanate on bile secretion prior to and during the onset of cholestasis in the rat

Lock, Simon, Lavigne, Jocelyn, Plaa, Gabriel L.

Journal:

Toxicology Letters

Year:

1982

Language:

english

File:

PDF, 577 KB

english, 1982

12

Relationship between the carbon skeleton length of ketonic solvents and potentiation of chloroform-induced hepatotoxicity in rats

Hewitt, William R., Brown, Esther M., Plaa, Gabriel L.

Journal:

Toxicology Letters

Year:

1983

Language:

english

File:

PDF, 537 KB

english, 1983

13

Pharmacological and Metabolic Interactions between Ethanol and Methyl n -Butyl Ketone, Methyl Isobutyl Ketone, Methyl Ethyl Ketone, or Acetone in Mice

CUNNINGHAM, JAMES, SHARKAWI, MAHMOUD, PLAA, GABRIEL L.

Journal:

Toxicological Sciences

Year:

1989

Language:

english

File:

PDF, 462 KB

english, 1989

14

Isopropanol and acetone potentiation of carbon tetrachloride‐induced hepatotoxic1ty: Single versus repetitive pretreatments in rats

Plaa, Gabriel L., Hewitt, William R., du Souich, Patrick, Caillé, Gilles, Lock, Simon

Journal:

Journal of Toxicology and Environmental Health

Year:

1982

Language:

english

File:

PDF, 991 KB

english, 1982

15

CCI 4 -Induced Liver Damage

Plaa, Gabriel L., Larson, Robert E.

Journal:

Archives of Environmental Health An International Journal

Year:

1964

Language:

english

File:

PDF, 2.06 MB

english, 1964

16

Correlation between acetone-potentiated CCl4-induced liver injury and blood concentrations after inhalation or oral administration

Michel Charbonneau, Jules Brodeur, Patrick du Souich, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 714 KB

english, 1986

17

Hepatic subcellular distribution of manganese in manganese and manganese-bilirubin induced cholestasis

Pierre Ayotte, Gabriel L. Plaa

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 962 KB

english, 1985

18

Delbert A. Greenwood

Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1973

Language:

english

File:

PDF, 341 KB

english, 1973

19

Quantitative and temporal delineation of various parameters of liver dysfunction due to α-naphthylisothiocyanate

Bernard A. Becker, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1965

Language:

english

File:

PDF, 773 KB

english, 1965

20

Effect of hypothermia on carbon tetrachloride-induced changes in hepatic ultrastructure

Christine Kurstak, Michel G. Côté, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1973

Language:

english

File:

PDF, 14.14 MB

english, 1973

21

EFFECT OF DOSING VEHICLE ON THE HEPATOTOXDCBTY OF CCl 4 AND NEPHROTOXICITY OF CHCl 3 IN RATS

Raymond, Pierre, Plaa, Gabriel L.

Journal:

Journal of Toxicology and Environmental Health

Year:

1997

Language:

english

File:

PDF, 701 KB

english, 1997

22

Temporal analysis of rat liver injury following potentiation of carbon tetrachloride hepatotoxicity with ketonic or ketogenic compounds

Michel Charbonneau, Moritake Iijima, Michel G. Côté, Gabriel L. Plaa

Journal:

Year:

1985

Language:

english

File:

PDF, 996 KB

english, 1985

23

Modification of biliary tree permeability in rats treated with a manganese-bilirubin combination

Pierre Ayotte, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 839 KB

english, 1986

24

Modifications in rat hepatobiliary function following treatment with acetone, 2-butanone, 2-hexanone, mirex, or chlordecone and subsequently exposed to chloroform

L.Arthur Hewitt, Pierre Ayotte, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 739 KB

english, 1986

25

Effect of isopropanol-induced potentiation of carbon tetrachloride on rat hepatic ultrastructure

Michel G. Côte, George J. Traiger, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1974

Language:

english

File:

PDF, 7.13 MB

english, 1974

26

The role of biotransformation–detoxication in acetone-, 2-butanone-, and 2-hexanone-potentiated chloroform-induced hepatotoxicity

Hewitt, L. Arthur, Valiquette, Céline, Plaa, Gabriel L.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1987

Language:

english

File:

PDF, 759 KB

english, 1987

27

Experimental Evaluation of Haloalkanes and Liver Injury

PLAA, GABRIEL L.

Journal:

Toxicological Sciences

Year:

1988

Language:

english

File:

PDF, 516 KB

english, 1988

28

Effect of inhibition of protein synthesis on cholestasis induced by taurolithocholate, lithocholate, and a manganese-bilirubin combination in the rat

Lena Dahlström-King, Gabriel L. Plaa

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 691 KB

english, 1989

29

Phase I and phase II metabolism of lithocholic acid in hepatic acinar zone 3 necrosis: Evaluation in rats by combined radiochromatography and gas-liquid chromatograpry-mass spectrometry

Serge Dionne, Beatriz Tuchweber, Gabriel L. Plaa, Ibrahim M. Yousef

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.83 MB

english, 1994

30

The effect of spinal cord transection on carbon tetrachloride hepatotoxicity

Robert E. Larson, Gabriel L. Plaa, Louis M. Crews

Journal:

Toxicology and Applied Pharmacology

Year:

1964

Language:

english

File:

PDF, 8.88 MB

english, 1964

31

The influence of severity of bile flow reduction, cycloheximide, and methyl isobutyl ketone pretreatment on the kinetics of taurolithocholic acid disposition in the rat

Lena Dahlström-King, Patrick du Souich, Johanne Couture, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 785 KB

english, 1990

32

Plasma disappearance and biliary excretion of indocyanine green in rats, rabbits, and dogs

Curtis D. Klaassen, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1969

Language:

english

File:

PDF, 615 KB

english, 1969

33

Relative effects of various chlorinated hydrocarbons on liver and kidney function in dogs

Curtis D. Klaassen, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1967

Language:

english

File:

PDF, 709 KB

english, 1967

34

Ketone Potentiation of Haloalkane-Induced Hepatotoxicity: CCl 4 and Ketone Treatment on Hepatic Membrane Integrity

Raymond, Pierre, Plaa, Gabriel L.

Journal:

Journal of Toxicology and Environmental Health

Year:

1996

Language:

english

File:

PDF, 1.45 MB

english, 1996

35

Methyl isobutyl ketone metabolites and potentiation of the cholestasis induced in rats by a manganese-bilirubin combination or manganese alone

Manon Vézina, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1988

Language:

english

File:

PDF, 702 KB

english, 1988

36

Functional changes of the biliary tree associated with experimentally induced cholestasis: Sulfobromophthalein on manganese-bilirubin combinations

Lena Dahlström-King, Johanne Couture, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1991

Language:

english

File:

PDF, 679 KB

english, 1991

37

Pathogenesis of lithocholate-induced intrahepatic cholestasis: Role of glucuronidation and hydroxylation of lithocholate

Dinh Duc Vu, Beatriz Tuchweber, Gabriel L. Plaa, Ibrahim M. Yousef

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1992

Language:

english

File:

PDF, 721 KB

english, 1992

38

Differences in the potentiation of carbon tetrachloride in rats by ethanol and isopropanol pretreatment

George J. Traiger, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1971

Language:

english

File:

PDF, 497 KB

english, 1971

39

Ketone potentiation of haloalkane‐induced hepato‐ and nephrotoxicity. I. dose‐response relationships

Raymond, Pierre, Plaa, Gabriel L.

Journal:

Journal of Toxicology and Environmental Health

Year:

1995

Language:

english

File:

PDF, 805 KB

english, 1995

40

Dose-Dependent Cytotoxicity of Chlorinated Hydrocarbons in Isolated Rat Hepatocytes

DAHLSTRÖM-KJNG, LENA, COUTURE, JOHANNE, LAMOUREUX, CLAUDETTE, VAILLANCOURT, THÉRÈSE, PLAA, GABRIEL L.

Journal:

Toxicological Sciences

Year:

1990

Language:

english

File:

PDF, 591 KB

english, 1990

41

Comparison of the biochemical alterations elicited in livers from rats treated with carbon tetrachloride, chloroform, 1,1,2-trichloroethaneand 1,1,1-trichloroethane

Curtis D. Klaassen, Gabriel L. Plaa

Journal:

Biochemical Pharmacology

Year:

1969

Language:

english

File:

PDF, 641 KB

english, 1969

42

Dose and time relationships in manganese-bilirubin cholestasis

Eve de Lamirande, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1979

Language:

english

File:

PDF, 568 KB

english, 1979

43

Catecholamine potentiation of carbon tetrachloride-induced hepatotoxicity in mice

Bernard A. Schwetz, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1969

Language:

english

File:

PDF, 1.07 MB

english, 1969

44

The nephrotoxicity of single and multiple doses of aliphatic chlorinated hydrocarbon solvents in male mice

William M. Watrous, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1972

Language:

english

File:

PDF, 878 KB

english, 1972

45

Role of perivenous hepatocytes in taurolithocholate-induced cholestasis in vivo

Aldo Mottino, Beatriz Tuchweber, Gabriel L Plaa, Ibrahim M Yousef

Journal:

Toxicology Letters

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

46

Effect of norethandrolone, acetohexamide, and enovid on α-naphthylisothiocyanate-induced hyperbilirubinemia and cholestasis

Robert J. Roberts, Gabriel L. Plaa

Journal:

Biochemical Pharmacology

Year:

1966

Language:

english

File:

PDF, 603 KB

english, 1966

47

Role of biotransformation in the alterations of chloroform hepatotoxicity produced by Kepone and mirex

Denis J. Cianflone, William R. Hewitt, David C. Villeneuve, Gabriel L. Plaa

Journal:

Toxicology and Applied Pharmacology

Year:

1980

Language:

english

File:

PDF, 904 KB

english, 1980

48

The effects of ethanol alone and in combination with phenobarbital, chlorpromazine, or chlordiazepoxide

Gerald F. Gebhart, Gabriel L. Plaa, C.L. Mitchell

Journal:

Toxicology and Applied Pharmacology

Year:

1969

Language:

english

File:

PDF, 731 KB

english, 1969

49

Dose-dependent modification of 1,1-dichloroethylene toxicity by acetone

Hewitt, William R., Plaa, Gabriel L.

Journal:

Toxicology Letters

Year:

1983

Language:

english

File:

PDF, 466 KB

english, 1983

50

The effects of oral diazepam pretreatment on the biliary excretion of sulfobromophthalein in rats

Hanasono, George K., Repentigny, Louis De, Priestly, Brian G., Plaa, Gabriel L.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1976

Language:

english

File:

PDF, 5.06 MB

english, 1976

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